Extra-corporeal detoxification in insects.

ABSTRACT: Upon uptake of toxins, insects launch a detoxification program. This program is deployed in multiple organs and cells to raise their tolerance against the toxin. The molecular mechanisms of this program inside the insect body have been studied and understood in detail. Here, we report on a yet unexplored extra-corporeal detoxification of insecticides in Drosophila melanogaster. Wild-type D. melanogaster incubated with DDT, a contact insecticide, in a closed environment died as expected. However, incubation of a second cohort in the same environment after removal of the dead flies was not lethal. The effect was significantly lower if the flies of the two cohorts were unrelated. Incubation assays with Chlorpyrifos, another contact insecticide, yielded identical results, while i

SUBMITTER: Yang J 

PROVIDER: S-EPMC10981100 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature