Butylphthalide combined with donepezil for the treatment of vascular dementia: a meta-analysis.

ABSTRACT:

Objective

To systematically evaluate the efficacy and safety of butylphthalide combined with donepezil versus butylphthalide monotherapy for the treatment of vascular dementia.

Methods

Randomized controlled trials were searched in electronic databases, including PubMed, Embase, the Cochrane Library, China National Knowledge Infrastructure, Chinese Science and Technology Periodical Database (VIP), Wan Fang, and China Biology Medicine from inception to 29 November 2022. Two reviewers independently screened the papers and extracted data from the included studies. The data were processed using RevMan5.4 statistical software.

Results

Nine randomized controlled trials (n = 1024) were included in this meta-analysis. Regarding the primary outcomes, compared with butylphthalid

SUBMITTER: Liu P 

PROVIDER: S-EPMC10981252 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature