The contribution of estimated dead space fraction to mortality prediction in patients with chronic obstructive pulmonary disease-a new proposal.

ABSTRACT:

Background

Mortality due to chronic obstructive pulmonary disease (COPD) is increasing. However, dead space fractions at rest (V_D/V_Trest) and peak exercise (V_D/V_Tpeak) and variables affecting survival have not been evaluated. This study aimed to investigate these issues.

Methods

This retrospective observational cohort study was conducted from 2010-2020. Patients with COPD who smoked, met the Global Initiatives for Chronic Lung Diseases (GOLD) criteria, had available demographic, complete lung function test (CLFT), medication, acute exacerbation of COPD (AECOPD), Charlson Comorbidity Index, and survival data were enrolled. V_D/V_Trest and V_D/V_Tpeak were estimated (estV_D/V_Tres

SUBMITTER: Chuang ML 

PROVIDER: S-EPMC10981412 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature