Perceived burden of respiratory physiotherapy in people with cystic fibrosis taking elexacaftor-tezacaftor-ivacaftor combination: a 1-year observational study.

ABSTRACT:

Background

To limit the progression of disease, people with cystic fibrosis (pwCF) perform daily respiratory physiotherapy, which is perceived as the most burdensome routine in managing their condition. The elexacaftor-tezacaftor-ivacaftor (ETI) combination has changed respiratory management.

Objective

To investigate how the perceived treatment burden changed in 1 year of treatment with ETI.

Design

Prospective observational study.

Methods

Ad hoc questionnaires for the pwCF and for the caregivers of pwCF < 18 years were administered before the initiation of ETI therapy and then at 6-12 months. The Cystic Fibrosis Questionnaire-Revised (CFQ-R) and the Sinonasal Outcome Test (SNOT-22) were administered to explore disease-related symptoms and social limitati

SUBMITTER: Blardone C 

PROVIDER: S-EPMC10981859 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature