Relationship between sodium level and in-hospital mortality in traumatic brain injury patients of MIMIC IV database.

ABSTRACT:

Background

An association between prognosis and high sodium levels in Traumatic Brain Injury (TBI) patients in Intensive Care Units (ICUs) has been noted, but limited research exists on the ideal sodium level in these patients or the impact on early mortality, using the MIMIC-IV database.

Methods

A retrospective survey was conducted on TBI patients from the MIMIC-IV database. Patients were divided into two categories based on their highest serum sodium level within 24 h of admission exceeding 145 mmol/L: those with hypernatremia, and those with moderate-to-low sodium levels. Collected covariates encompasses demographic, clinical, laboratory, and intervention variables. A multivariate logistic regression model was implemented to forecast in-hospital mortality.

Results

SUBMITTER: Wang X 

PROVIDER: S-EPMC10982354 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature