The relationship between autoimmune thyroid disease, thyroid nodules and sleep traits: a Mendelian randomization study.

ABSTRACT:

Background

Previous studies have suggested a potential association between Autoimmune thyroid disease Thyroid nodules and Sleep Traits, but the evidence is limited and controversial, and the exact causal relationship remains uncertain.

Objective

Therefore, we employed a MR analysis to investigate the causal relationship between Autoimmune thyroid disease, Thyroid nodules and Sleep Traits.

Methods

To explore the interplay between Autoimmune thyroid disease Thyroid nodules and Sleep Traits, we employed MR studies utilizing summary statistics derived from GWAS in individuals of European ancestry. To ensure robustness, multiple techniques were employed to assess the stability of the causal effect, including random-effect inverse variance weighted, weighted median, MR-Egge

SUBMITTER: Wang S 

PROVIDER: S-EPMC10982365 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature