Synthesis and biological evaluation of novel benzothiazole derivatives as potential anticancer and antiinflammatory agents.

ABSTRACT: Introduction: Cancer, a significant global health concern, necessitates innovative treatments. The pivotal role of chronic inflammation in cancer development underscores the urgency for novel therapeutic strategies. Benzothiazole derivatives exhibit promise due to their distinctive structures and broad spectrum of biological effects. This study aims to explore new anti-tumor small molecule drugs that simultaneously anti-inflammatory and anticancer based on the advantages of benzothiazole frameworks. Methods: The compounds were characterized by nuclear magnetic resonance (NMR), liquid chromatograph-mass spectrometer (LC-MS) and high performance liquid chromatography (HPLC) for structure as well as purity and other related physicochemical properties. The effects of the compound

SUBMITTER: Xu X 

PROVIDER: S-EPMC10982501 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature