Efficacy and safety of terlipressin infusion during liver surgery: a protocol for systematic review and meta-analysis.

ABSTRACT:

Introduction

Liver disease causes 2 million deaths annually, accounting for 4% of all deaths worldwide. Liver surgery is one of the effective therapeutic options. Bleeding is a major complication during liver surgery. Perioperative bleeding and allogeneic blood transfusion may deteriorate the prognosis. Terlipressin (TP), a synthetic analogue of the antidiuretic hormone, may reduceblood loss during abdominal surgery. Several clinical centres have attempted to use TP during liver surgery, but the evidence for its effectiveness in reducing blood loss and the need for allogeneic blood transfusion, as well as its safety during the perioperative period, remains unclear. The aim of this systematic review and meta-analysis is to evaluate the efficacy and safety of TP in reducing blood los

SUBMITTER: Ding L 

PROVIDER: S-EPMC10982717 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature