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Lifestyle-related factors in late midlife as predictors of frailty from late midlife into old age: a longitudinal birth cohort study.


ABSTRACT:

Background

Few studies have examined longitudinal changes in lifestyle-related factors and frailty.

Methods

We examined the association between individual lifestyle factors (exercise, diet, sleep, alcohol, smoking and body composition), their sum at baseline, their change over the 17-year follow-up and the rate of change in frailty index values using linear mixed models in a cohort of 2,000 participants aged 57-69 years at baseline.

Results

A higher number of healthy lifestyle-related factors at baseline was associated with lower levels of frailty but not with its rate of change from late midlife into old age. Participants who stopped exercising regularly (adjusted β × Time = 0.19, 95%CI = 0.10, 0.27) and who began experiencing sleeping difficulties (adjusted β × Time

SUBMITTER: Haapanen MJ 

PROVIDER: S-EPMC10982848 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature