Moving toward precision medicine to predict drug sensitivity in patients with metastatic breast cancer.

ABSTRACT: Tumor heterogeneity represents a major challenge in breast cancer, being associated with disease progression and treatment resistance. Precision medicine has been extensively applied to dissect tumor heterogeneity and, through a deeper molecular understanding of the disease, to personalize therapeutic strategies. In the last years, technological advances have widely improved the understanding of breast cancer biology and several trials have been developed to translate these new insights into clinical practice, with the ultimate aim of improving patients' outcomes. In the era of molecular oncology, genomics analyses and other methodologies are shaping a new treatment algorithm in breast cancer care. In this manuscript, we review the main steps of precision medicine to predict drug sensitivi

SUBMITTER: Bottosso M 

PROVIDER: S-EPMC10982863 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature