Imbalance of gut microbiota in gestational diabetes.

ABSTRACT:

Aim

To investigate the differences in gut microbiota composition among nonpregnant women of reproductive age, healthy pregnant women, and gestational diabetes (GD) patients.

Methods

A total of 45 outpatients were enrolled and divided into three groups: nonpregnant women of reproductive age (control group, n = 23), healthy pregnant women (normal group, n = 10), and GD patients (GD group, n = 12). Faecal samples were collected and sequenced using 16S rRNA gene sequencing to analyse the microbial composition.

Results

(1) Pregnant patients exhibited an increase in the abundance of Streptococcus (P_normal = 0.01286, P_GD = 0.002965) and Blautia (P_normal = 0.0003924, P_GD = 0.000246) but a decrease in the abundance of Roseburia (P

SUBMITTER: Shen W 

PROVIDER: S-EPMC10983739 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature