The development and external validation of a web-based nomogram for predicting overall survival with Ewing sarcoma in children.

ABSTRACT:

Background

Ewing sarcoma remains the second most prevalent primary aggressive bone tumor in teens and young adults. The aim of our study was to develop and validate a web-based nomogram to predict the overall survival for Ewing sarcoma in children.

Methods

A total of 698 patients, with 640 cases from the Surveillance, Epidemiology, and End Results (the training set) and 58 cases (the external validation set), were included in this study. Cox analyses were carried out to determine the independent prognostic indicators, which were further included to establish a web-based nomogram. The predictive abilities were tested through the concordance index, calibration curve, decision curve analysis, and area under the receiver operating characteristic curve.

Results

As suggeste

SUBMITTER: Chen Y 

PROVIDER: S-EPMC10984150 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature