Brain function abnormalities and neuroinflammation in people living with HIV-associated anxiety disorders.

ABSTRACT:

Background

People living with HIV (PLWH) exhibits an increased susceptibility to anxiety disorders, concomitant with heightened vulnerability to aberrant immune activation and inflammatory responses, and endocrine dysfunction. There exists a dearth of scholarly investigations pertaining to the neurological, immune, and endocrine dimensions of HIV-associated anxiety disorders.

Method

This study aimed to compare a group of 16 individuals diagnosed with HIV-associated anxiety disorders (HIV ANXs) according to the Diagnostic and statistical manual of mental disorders (5th ed.), with a HIV individual control group (HIV control) of 49 PLWH without mental disorders. Muti-modal magnetic resonance was employed to assess the brain function and structure of both groups. Seed-based func

SUBMITTER: Shan Y 

PROVIDER: S-EPMC10984160 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature