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ABSTRACT:
SUBMITTER: Tsubouchi A
PROVIDER: S-EPMC10985231 | biostudies-literature | 2024 Mar
REPOSITORIES: biostudies-literature
Tsubouchi Asako A An Yuri Y Kawamura Yoko Y Yanagihashi Yuichi Y Nakayama Hirofumi H Murata Yuri Y Teranishi Kazuki K Ishiguro Soh S Aburatani Hiroyuki H Yachie Nozomu N Ota Sadao S
Cell reports methods 20240301 3
Recent advancements in image-based pooled CRISPR screening have facilitated the mapping of diverse genotype-phenotype associations within mammalian cells. However, the rapid enrichment of cells based on morphological information continues to pose a challenge, constraining the capacity for large-scale gene perturbation screening across diverse high-content cellular phenotypes. In this study, we demonstrate the applicability of multimodal ghost cytometry-based cell sorting, including both fluoresc ...[more]