Association between amino acids and recent osteoporotic fracture: a matched incident case-control study.

ABSTRACT:

Context

Osteoporotic fracture is a major public health issue globally. Human research on the association between amino acids (AAs) and fracture is still lacking.

Objective

To examine the association between AAs and recent osteoporotic fractures.

Methods

This age and sex matched incident case-control study identified 44 recent x-ray confirmed fracture cases in the Second Hospital of Jilin University and 88 community-based healthy controls aged 50+ years. Plasma AAs were measured by high performance liquid chromatography coupled with mass spectrometry. After adjusting for covariates (i.e., body mass index, milk intake >1 time/week, falls and physical activity), we conducted conditional logistical regression models to test the association between AAs and fracture.

Res

SUBMITTER: Liang B 

PROVIDER: S-EPMC10985241 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature