Case report: Avoiding intolerance to antipsychotics through a personalized treatment approach based on pharmacogenetics.

ABSTRACT:

Introduction

The standard approach to treatment in psychiatry is known as "treatment as usual" (TAU), in which the same types of treatment are administered to a group of patients. TAU often requires numerous dose adjustments and medication changes due to ineffectiveness and/or the occurrence of adverse drug reactions (ADRs). This process is not only time-consuming but also costly. Antipsychotic medications are commonly used to treat various psychiatric disorders such as schizophrenia and mood disorders. Some of the inter-individual differences in efficacy and ADRs observed in psychopharmacotherapy can be explained by genetic variability in the pharmacokinetics and pharmacodynamics of antipsychotics. A better understanding of (in)efficacy and possible ADRs can be achieved by pharmac

SUBMITTER: Korosec Hudnik L 

PROVIDER: S-EPMC10985247 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature