Ontology highlight
ABSTRACT:
SUBMITTER: Floch A
PROVIDER: S-EPMC10985258 | biostudies-literature | 2024
REPOSITORIES: biostudies-literature
Floch Aline A Galochkina Tatiana T Pirenne France F Tournamille Christophe C de Brevern Alexandre G AG
Frontiers in chemistry 20240319
<b>Introduction:</b> Blood group antigens of the RH system (formerly known as "Rhesus") play an important role in transfusion medicine because of the severe haemolytic consequences of antibodies to these antigens. No crystal structure is available for RhD proteins with its partner RhAG, and the precise stoichiometry of the trimer complex remains unknown. <b>Methods:</b> To analyse their structural properties, the trimers formed by RhD and/or RhAG subunits were generated by protein modelling and ...[more]