Venous thromboembolism chemical prophylaxis after skull base surgery.

ABSTRACT:

Purpose

There is no guidance surrounding postoperative venous thromboembolism (VTE) prophylaxis using pharmacological agents (chemoprophylaxis) in patients undergoing skull base surgery. The aim of this study was to compare VTE and intracranial haematoma rates after skull base surgery in patients treated with/without chemoprophylaxis.

Methods

Review of prospective quaternary centre database including adults undergoing first-time skull base surgery (2009-2020). VTE was defined as deep vein thrombosis (DVT) and pulmonary embolism (PE) within 6 months of surgery. Multivariate logistic regression was used to determine factors predictive of postoperative intracranial haematoma/VTE. Propensity score matching (PSM) was used in group comparisons.

Results

One thousand five hun

SUBMITTER: Waqar M 

PROVIDER: S-EPMC10987339 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature