A new clinical model for predicting lymph node metastasis in T1 colorectal cancer.

ABSTRACT:

Purpose

Lymph node metastasis (LNM) is a crucial factor that determines the prognosis of T1 colorectal cancer (CRC) patients. We aimed to develop a practical prediction model for LNM in T1 CRC.

Methods

We conducted a retrospective analysis of data from 825 patients with T1 CRC who underwent radical resection at a single center in China. All enrolled patients were randomly divided into a training set and a validation set at a ratio of 7:3 using R software. Risk factors for LNM were identified through multivariate logistic regression analyses. Subsequently, a prediction model was developed using the selected variables.

Results

The lymph node metastasis (LNM) rate was 10.1% in the training cohort and 9.3% in the validation cohort. In the training set, risk factors for LN

SUBMITTER: Wang K 

PROVIDER: S-EPMC10987358 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature