Study on the causal relationship between educational attainment and delirium: A two-sample Mendelian randomization study.

ABSTRACT: This study aimed to investigate whether there is a causal relationship between educational attainment and delirium at the genetic level using the Mendelian randomization method, and provide new evidence for studies in this field. We found a causal relationship between educational attainment and delirium at the genetic level after excluding confounders using Mendelian randomization. The inverse variance weighting method of random effects was the main analysis method. The weighted median and Mendelian Randomization-Egger methods, as well as simple, and weighted modes were used as supplementary analysis methods. Additionally, horizontal pleiotropy tests were conducted, including the Mendelian Randomization-Egger intercept test and Mendelian Randomization Pleiotropy RESidual Sum and Outlier. C

SUBMITTER: Wan X 

PROVIDER: S-EPMC10988048 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature