Nanoscale solvent organization in metal-organic framework ZIF-8 probed by EPR of flexible β-phosphorylated nitroxides.

ABSTRACT: Metal-organic frameworks (MOFs) draw increasing attention as nanoenvironments for chemical reactions, especially in the field of catalysis. Knowing the specifics of MOF cavities is decisive in many of these cases; yet, obtaining them in situ remains very challenging. We report the first direct assessment of the apparent polarity and solvent organization inside MOF cavities using a dedicated structurally flexible spin probe. A stable β-phosphorylated nitroxide radical was incorporated into the cavities of a prospective MOF ZIF-8 in trace amounts. The spectroscopic properties of this probe depend on local polarity, structuredness, stiffness and cohesive pressure and can be precisely monitored by Electron Paramagnetic Resonance (EPR) spectroscopy. Using this approach, we have demonstra

SUBMITTER: Poryvaev AS 

PROVIDER: S-EPMC10988587 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature