Association between hypomagnesemia and serum lactate levels in patients with sepsis: a retrospective observational study.

ABSTRACT:

Background

Sepsis-3 emphasizes the recognition of sepsis-induced cellular metabolic abnormalities, and utilizes serum lactate level as a biomarker of cellular metabolic abnormalities. Magnesium plays an important role as a cofactor in glucose metabolism, although it is not well known that magnesium deficiency causes elevated serum lactate levels. Additionally, it remains unclear how magnesium status affects the role of serum lactate levels as a marker of metabolic abnormalities in sepsis. Thus, this study aimed to investigate the association between serum magnesium and lactate levels in patients with sepsis and explore this relationship from the perspectives of time course and circulatory abnormalities.

Methods

This retrospective observational study of adult patients with se

SUBMITTER: Tonai K 

PROVIDER: S-EPMC10988873 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature