Atmospheric-pressure scanning microprobe matrix-assisted laser desorption/ionization mass spectrometry imaging of Neospora caninum-infected cell monolayers.

ABSTRACT: Neospora caninum is an obligate intracellular protozoan parasite of the phylum Alveolata (subphylum Apicomplexa) which has not been studied extensively in a biochemical context. N. caninum is a primary cause of reproductive disorders causing mummification and abortion not only in cattle but also in other small ruminant species resulting in a substantial economic impact on the livestock industry. In canids, which are the final hosts of N. caninum, clinical disease includes neuromuscular symptoms, ataxia, and ascending paralysis. Fatal outcomes of neosporosis have also been reported depending on the host species, age and immune status, however, its zoonotic potential is still uncertain. Therefore, N. caninum should be thoroughly investigated. Matrix-assisted laser

SUBMITTER: Anschutz NH 

PROVIDER: S-EPMC10989629 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature