Association between hemoglobin trajectories and the incidence of dementia in a cohort of females aged 55-79 years.

ABSTRACT:

Purpose

To assess the association between pattern changes in hemoglobin levels over time and the incidence of dementia using trajectories in females aged 55-79 years.

Materials and methods

We conducted a retrospective cohort study using females of aged 55-79 years from the National Health Insurance Service National Health Screening Cohort in Korea. To identify hemoglobin trajectories over eight years (2002-2009), we performed a three-step approach comprising measures of change, factor analysis, and cluster analysis. Univariate and multivariate Cox proportional hazard models were used to assess the associations between hemoglobin trajectories and the incidence of dementia.

Results

We included 20,195 of 235,742 female participants. New dementia (N = 2664) was developed

SUBMITTER: Lee DY 

PROVIDER: S-EPMC10990242 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature