Diet-induced ketosis in adult patients with subacute acquired brain injury: a feasibility study.

ABSTRACT:

Background

Research in animal models on cerebral metabolism after brain injury highlights the potential benefits of ketosis in reducing secondary brain injury, but studies in humans are lacking.

Aim

This study aimed to examine if a 6-week ketogenic diet intervention with added medium-chain triglycerides (MCT) was feasible in adult patients with acquired brain injury in the subacute phase, whether ketosis could be achieved and maintained, and to what extent serious adverse reactions, adverse reactions, serious adverse events, and adverse events occured.

Methods

Patients ≥18 years of age diagnosed with subacute acquired brain injury and an expectation of hospitalisation ≥6 weeks were included in the intervention group. Patients not included in the intervention group wer

SUBMITTER: Edwards MGP 

PROVIDER: S-EPMC10990248 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature