Ocular dominance-dependent binocular combination of monocular neuronal responses in macaque V1.

ABSTRACT: Primates rely on two eyes to perceive depth, while maintaining stable vision when either one eye or both eyes are open. Although psychophysical and modeling studies have investigated how monocular signals are combined to form binocular vision, the underlying neuronal mechanisms, particularly in V1 where most neurons exhibit binocularity with varying eye preferences, remain poorly understood. Here, we used two-photon calcium imaging to compare the monocular and binocular responses of thousands of simultaneously recorded V1 superficial-layer neurons in three awake macaques. During monocular stimulation, neurons preferring the stimulated eye exhibited significantly stronger responses compared to those preferring both eyes. However, during binocular stimulation, the responses of neurons prefer

SUBMITTER: Zhang SH 

PROVIDER: S-EPMC10990486 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature