Comparison of phenomic profiles in the All of Us Research Program against the US general population and the UK Biobank.

ABSTRACT:

Importance

Knowledge gained from cohort studies has dramatically advanced both public and precision health. The All of Us Research Program seeks to enroll 1 million diverse participants who share multiple sources of data, providing unique opportunities for research. It is important to understand the phenomic profiles of its participants to conduct research in this cohort.

Objectives

More than 280 000 participants have shared their electronic health records (EHRs) in the All of Us Research Program. We aim to understand the phenomic profiles of this cohort through comparisons with those in the US general population and a well-established nation-wide cohort, UK Biobank, and to test whether association results of selected commonly studied diseases in the All of Us cohort were co

SUBMITTER: Zeng C 

PROVIDER: S-EPMC10990551 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature