Associations of Combined Exposure to Metabolic and Inflammatory Indicators with Thyroid Nodules in Adults: A Nested Case-Control Study.

ABSTRACT:

Objective

To explore associations of combined exposure to metabolic/inflammatory indicators with thyroid nodules.

Methods

We reviewed personal data for health screenings from 2020 to 2021. A propensity score matching method was used to match 931 adults recently diagnosed with thyroid nodules in a 1 : 4 ratio based on age and gender. Conditional logistic regression and Bayesian kernel machine regression (BKMR) were used to explore the associations of single metabolic/inflammatory indicators and the mixture with thyroid nodules, respectively.

Results

In the adjusted models, five indicators (OR_{Q4 vs. Q1}: 1.30, 95% CI: 1.07-1.58 for fasting blood glucose; OR_{Q4 vs. Q1}: 1.30, 95% CI: 1.08-1.57 for systolic blood pressure; OR_{Q4 vs. Q1}: 1.26,

SUBMITTER: Zhu XY 

PROVIDER: S-EPMC10990645 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature