Associations between Plasma Tocopherols and Lung Cancer Risk: Results from the Southern Community Cohort Study.

ABSTRACT:

Background

Despite the various anticancer activities of tocopherols, little is known about tocopherols associated with lung cancer risk among low-income African Americans (AA) and European Americans (EA) who are disproportionately affected by the disease.

Methods

We conducted a nested case-control study that included 209 incident lung cancer cases and 406 matched controls within the Southern Community Cohort Study. Using biospecimens collected at cohort enrollment, plasma levels of α-, β/γ-, δ-, and total-tocopherols were measured by high-performance liquid chromatography with photodiode array detection. Conditional logistic regression was used to estimate ORs and 95% confidence intervals (CI) for lung cancer risk after adjusting for potential confounders. Stratified analyse

SUBMITTER: Yoon HS 

PROVIDER: S-EPMC10990776 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature