Biomarkers and sepsis severity as predictors of mechanical ventilation and mortality in COVID-19.

ABSTRACT:

Introduction

Patients with septic shock face an elevated risk of mortality compared to those with sepsis. Several biomarkers, including lactate dehydrogenase, albumin, and lactate/albumin (L/A), have been associated with increased mortality in COVID-19 patients. This study aims to assess the relationship between sepsis, septic shock, and mortality, as well as the need for mechanical ventilation in COVID-19 patients. Demographic, sepsis severity factors, and biomarkers are examined.

Methods

A retrospective case series from June 2020 to March 2021 included 490 patients diagnosed with sepsis or septic shock secondary to SARS-CoV-2 pneumonia. Time-to-event analyses were conducted for mechanical ventilation and mortality. Statistical significance was set at p ≤ .0038. Serum lacta

SUBMITTER: Jimenez-Zarazua O 

PROVIDER: S-EPMC10990852 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature