Selfish conflict underlies RNA-mediated parent-of-origin effects.

ABSTRACT: Genomic imprinting-the non-equivalence of maternal and paternal genomes-is a critical process that has evolved independently in many plant and mammalian species^1,2. According to kinship theory, imprinting is the inevitable consequence of conflictive selective forces acting on differentially expressed parental alleles^3,4. Yet, how these epigenetic differences evolve in the first place is poorly understood^3,5,6. Here we report the identification and molecular dissection of a parent-of-origin effect on gene expression that might help to clarify this fundamental question. Toxin-antidote elements (TAs) are selfish elements that spread in populations by poisoning non-carrier individuals^7-9. In reciprocal crosses between two Caenorhabditis tropicalis wi

SUBMITTER: Pliota P 

PROVIDER: S-EPMC10990930 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature