Weissella sp. SNUL2 as potential probiotics with broad-spectrum antimicrobial activities.

ABSTRACT: Probiotics have been applied to a wide range of bacteria, causing gastrointestinal and vaginal infections. However, probiotics generally possess limited antimicrobial spectra and are primarily utilized as dietary supplements. Recognizing the need for more versatile probiotics, this study focuses on isolating and characterizing strains suitable for antibiotic replacement. Among these strains, Weissella sp. SNUL2, derived from a traditional fermented food in Korea (i.e., Sikhae), emerged as a promising candidate. The correlation between optical density at 600 nm and colony-forming units was verified and applied in subsequent experiments. To assess the therapeutic potential of probiotics, antibacterial tests were conducted using a microplate reader to evaluate the inhibition of 60 bact

SUBMITTER: Han JW 

PROVIDER: S-EPMC10990963 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature