Stressing out-carp edema virus induces stress and modulates immune response in common carp.

ABSTRACT:

Introduction

Carp edema virus (CEV) is a fish poxvirus that primarily infects the gills of common carp. CEV causes koi sleepy disease (KSD), which is highly contagious and can result in mortality of up to 100%.

Methods

In the present study, we analyzed the stress and immune responses during KSD in two strains of common carp with different resistance to CEV: susceptible koi and resistant Amur sazan. Experiments were performed at two temperatures: 12°C and 18°C. In the case of koi carp, we also analyzed the effect of supplementation of 0.6% NaCl into tank water, which prevents mortality of the CEV-infected fish (salt rescue model).

Results

We found that CEV-infected koi kept at 18°C had the highest viral load, which correlated with the most severe histopathological chan

SUBMITTER: Zawisza M 

PROVIDER: S-EPMC10991768 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature