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Immune system dysregulation preceding a case of laboratory-confirmed zoster/dermatitis on board the International Space Station.

ABSTRACT: A case report detailing, for the first time, a case of laboratory-confirmed zoster in an astronaut on board the International Space Station is presented. The findings of reduced T-cell function, cytokine imbalance, and increased stress hormones which preceded the event are detailed. Relevance for deep space countermeasures is discussed.

SUBMITTER: Mehta SK

PROVIDER: S-EPMC10992860 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature

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Immune system dysregulation preceding a case of laboratory-confirmed zoster/dermatitis on board the International Space Station.

Mehta Satish K SK Suresh Rahul R Brandt Keith K Diak Douglass M DM Smith Scott M SM Zwart Sara R SR Douglas Grace G Nelman-Gonzalez Mayra M Clemett Simon S Brunstetter Tyson T Crucian Brian E BE

The journal of allergy and clinical immunology. Global 20240313 2

A case report detailing, for the first time, a case of laboratory-confirmed zoster in an astronaut on board the International Space Station is presented. The findings of reduced T-cell function, cytokine imbalance, and increased stress hormones which preceded the event are detailed. Relevance for deep space countermeasures is discussed. ...[more]

PMID: 38577482

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