Endothelial shear stress computed from coronary computed tomography angiography: A direct comparison to intravascular ultrasound.

ABSTRACT:

Introduction

Intravascular ultrasound (IVUS) studies have shown that biomechanical variables, particularly endothelial shear stress (ESS), add synergistic prognostic insight when combined with anatomic high-risk plaque features. Non-invasive risk assessment of coronary plaques with coronary computed tomography angiography (CCTA) would be helpful to enable broad population risk-screening.

Aim

To compare the accuracy of ESS computation of local ESS metrics by CCTA vs IVUS imaging.

Methods

We analyzed 59 patients from a registry of patients who underwent both IVUS and CCTA for suspected CAD. CCTA images were acquired using either a 64- or 256-slice scanner. Lumen, vessel, and plaque areas were segmented from both IVUS and CCTA (59 arteries, 686 3-mm segments). Images wer

SUBMITTER: Hakim D 

PROVIDER: S-EPMC10993230 | biostudies-literature | 2023 May-Jun

REPOSITORIES: biostudies-literature