Comparative analysis of microbial composition and functional characteristics in dental plaque and saliva of oral cancer patients.

ABSTRACT:

Background

The oral cavity is home to various ecological niches, each with its own unique microbial composition. Understanding the microbial communities and gene composition in different ecological niches within the oral cavity of oral cancer (OC) patients is crucial for determining how these microbial populations contribute to disease progression.

Methods

In this study, saliva and dental plaque samples were collected from patients with OC. Metagenomic sequencing was employed to analyze the microbial community classification and functional composition of the different sample groups.

Results

The results of the study revealed significant differences in both the function and classification of microbial communities between saliva and dental plaque samples. The diversity o

SUBMITTER: Zhang M 

PROVIDER: S-EPMC10993480 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature