Mass Relapse Prevention to Reduce Transmission of Plasmodium vivax- A Systematic Review.

ABSTRACT: Several temperate countries have used mass chemoprevention interventions with medicines of the 8-aminoquinoline class that prevent relapses from Plasmodium vivax before peak transmission to reduce transmission of malaria. The WHO commissioned a systematic review of the literature and evidence synthesis to inform development of recommendations regarding this intervention referred to as "mass relapse prevention" (MRP). Electronic databases were searched, 866 articles screened, and 25 assessed for eligibility after a full-text review. Two nonrandomized studies were included, one from the Democratic People's Republic of Korea (391,357 participants) and the second from the Azerbaijan Soviet Socialist Republic (∼30,000 participants). The two studies administered a single round of primaquine over

SUBMITTER: Shah MP 

PROVIDER: S-EPMC10993785 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature