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Targeted Drug Administration to Reduce Malaria Transmission: A Systematic Review and Meta-Analysis.


ABSTRACT: In low- to very low-malaria transmission areas, most infections may be accrued within specific groups whose behaviors or occupations put them at increased risk of infection. If these infections comprise a large proportion of the reservoir of infection, targeting interventions to these groups could reduce transmission at the population level. We conducted a systematic review to assess the impact of providing antimalarials to groups of individuals at increased risk of malaria whose infections were considered to comprise a large proportion of the local reservoir of infections (targeted drug administration [TDA]). A literature search was conducted in March 2021 and updated in April 2022. Two reviewers screened titles, abstracts, and full-text records. The Grading of Recommendations Assessment,

SUBMITTER: Tusell M 

PROVIDER: S-EPMC10993794 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature