EMinsight: a tool to capture cryoEM microscope configuration and experimental outcomes for analysis and deposition.

ABSTRACT: The widespread adoption of cryoEM technologies for structural biology has pushed the discipline to new frontiers. A significant worldwide effort has refined the single-particle analysis (SPA) workflow into a reasonably standardized procedure. Significant investments of development time have been made, particularly in sample preparation, microscope data-collection efficiency, pipeline analyses and data archiving. The widespread adoption of specific commercial microscopes, software for controlling them and best practices developed at facilities worldwide has also begun to establish a degree of standardization to data structures coming from the SPA workflow. There is opportunity to capitalize on this moment in the maturation of the field, to capture metadata from SPA experiments and correlate

SUBMITTER: Hatton D 

PROVIDER: S-EPMC10994178 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature