Higher serum alanine aminotransferase levels and the incidence of hypertension: The Kailuan cohort study.

ABSTRACT:

Objective

The association between serum alanine aminotransferase (ALT) concentrations and the incidence of hypertension remains unclear. To explore the association between serum ALT levels and the risk of incident hypertension based on the Kailuan cohort study.

Methods

People who had participated in health check-ups in 2006-2007 without hypertension, cardiovascular, or liver diseases were enrolled and received follow-ups every two years until December 2017. Hypertension was defined as systolic blood pressure/diastolic blood pressure ≥140/90 mmHg or using anti-hypertensive medication. A multivariable-adjusted Cox regression model was used to estimate the hazard ratio (HR) and its corresponding 95 % confidence intervals (95 % CIs).

Results

During 10.5 years of follow-up

SUBMITTER: Jia J 

PROVIDER: S-EPMC10994974 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature