Unknown

Dataset Information

0

Fast online spectral-spatial pulse design for subject-specific fat saturation in cervical spine and foot imaging at 1.5 T.


ABSTRACT:

Objective

To compensate subject-specific field inhomogeneities and enhance fat pre-saturation with a fast online individual spectral-spatial (SPSP) single-channel pulse design.

Methods

The RF shape is calculated online using subject-specific field maps and a predefined excitation k-space trajectory. Calculation acceleration options are explored to increase clinical viability. Four optimization configurations are compared to a standard Gaussian spectral selective pre-saturation pulse and to a Dixon acquisition using phantom and volunteer (N = 5) data at 1.5 T with a turbo spin echo (TSE) sequence. Measurements and simulations are conducted across various body parts and image orientations.

Results

Phantom measurements demonstrate up to a 3.5-fold reduction in residual fat signal compared to Gaussian fat saturation. In vivo evaluations show improvements up to sixfold for dorsal subcutaneous fat in sagittal cervical spine acquisitions. The versatility of the tailored trajectory is confirmed through sagittal foot/ankle, coronal, and transversal cervical spine experiments. Additional measurements indicate that excitation field (B1) information can be disregarded at 1.5 T. Acceleration methods reduce computation time to a few seconds.

Discussion

An individual pulse design that primarily compensates for main field (B0) inhomogeneities in fat pre-saturation is successfully implemented within an online "push-button" workflow. Both fat saturation homogeneity and the level of suppression are improved.

SUBMITTER: Eisen CK 

PROVIDER: S-EPMC10995033 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature

altmetric image

Publications

Fast online spectral-spatial pulse design for subject-specific fat saturation in cervical spine and foot imaging at 1.5 T.

Eisen Christian Karl CK   Liebig Patrick P   Herrler Jürgen J   Ritter Dieter D   Lévy Simon S   Uder Michael M   Nagel Armin Michael AM   Grodzki David D  

Magma (New York, N.Y.) 20240217 2


<h4>Objective</h4>To compensate subject-specific field inhomogeneities and enhance fat pre-saturation with a fast online individual spectral-spatial (SPSP) single-channel pulse design.<h4>Methods</h4>The RF shape is calculated online using subject-specific field maps and a predefined excitation k-space trajectory. Calculation acceleration options are explored to increase clinical viability. Four optimization configurations are compared to a standard Gaussian spectral selective pre-saturation pul  ...[more]

Similar Datasets

| S-EPMC9045927 | biostudies-literature
| S-EPMC11771585 | biostudies-literature
| S-EPMC9108519 | biostudies-literature
| S-EPMC10439925 | biostudies-literature
| S-EPMC4542156 | biostudies-literature
| S-EPMC8246263 | biostudies-literature
| S-EPMC1426241 | biostudies-literature
| S-EPMC6492254 | biostudies-literature
| S-EPMC7154345 | biostudies-literature
| S-EPMC8057527 | biostudies-literature