The influence of the precuneus on the medial temporal cortex determines the subjective quality of memory during the retrieval of naturalistic episodes.

ABSTRACT: Memory retrieval entails dynamic interactions between the medial temporal lobe and areas in the parietal and frontal cortices. Here, we tested the hypothesis that effective connectivity between the precuneus, in the medial parietal cortex, and the medial temporal cortex contributes to the subjective quality of remembering objects together with information about their rich spatio-temporal encoding context. During a 45 min encoding session, the participants were presented with pictures of objects while they actively explored a virtual town. The following day, under fMRI, participants were presented with images of objects and had to report whether: they recognized the object and could remember the place/time of encoding, the object was familiar only, or the object was new. The hippocampus/par

SUBMITTER: Foudil SA 

PROVIDER: S-EPMC10995201 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature