The burden of frailty in heart failure: Prevalence, impacts on clinical outcomes and the role of heart failure medications.

ABSTRACT:

Background

Frailty often coexists with heart failure (HF), which significantly aggravates the clinical outcomes of older adults. However, studies investigating the interplay between frailty and HF in older adults are scarce. We aimed to assess the prevalence of frailty using the cumulative deficit approach and evaluate the impacts of frailty on health utilization, use of HF-related medications and adverse clinical outcomes (all-cause mortality, all-cause readmissions and HF readmissions) among older HF patients.

Methods

A total of 38 843 newly admitted HF patients were identified from Taiwan's National Health Insurance Research Database and categorized into three frailty subgroups (fit, mild frailty and severe frailty) based on the multimorbidity frailty index. Cox regressio

SUBMITTER: Lai HY 

PROVIDER: S-EPMC10995260 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature