Risk factors for suicidal attempts in a sample of outpatients with treatment-resistant depression: an observational study.

ABSTRACT:

Introduction

Treatment-resistant depression (TRD) is commonly defined as the failure of at least two trials with antidepressant drugs, given at the right dose and for an appropriate duration. TRD is associated with increased mortality, compared to patients with a simple major depressive episode. This increased rate was mainly attributed to death from external causes, including suicide and accidents. The aim of our study is to identify socio-demographic and psychopathological variables associated with suicidal attempts in a sample of outpatients with TRD.

Material and methods

We performed a monocentric observational study with a retrospective design including a sample of 63 subjects with TRD referred to an Italian outpatient mental health centre. We collected socio-demographi

SUBMITTER: Civardi SC 

PROVIDER: S-EPMC10995380 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature