The role of online hemodiafiltration with endogenous reinfusion in the treatment of systemic lupus erythematosus activity resistant to conventional therapy.

ABSTRACT:

Introduction

Lupus is a diverse autoimmune disease with autoantibody formation. Lupus nephritis carries a grave prognosis. Complement involvement, namely, C1q deficiency, is linked to activity and renal involvement and could help in their assessment. LN therapies include plasma exchange, immune adsorption, and probably hemodiafiltration with online endogenous reinfusion (HFR), together with traditional immunosuppressive therapies.

Aim

The aim of this study was to evaluate the role of HFR in improving signs and symptoms of systemic lupus erythematosus (SLE) activity and laboratory parameters in cases not responding to traditional immunosuppressive therapy.

Settings and design

A controlled clinical study was conducted on 60 patients with lupus from Group A that was subd

SUBMITTER: Elghiriani MA 

PROVIDER: S-EPMC10995452 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature