Skin Barrier Function Assessment: Electrical Impedance Spectroscopy Is Less Influenced by Daily Routine Activities Than Transepidermal Water Loss.

ABSTRACT:

Background

Skin barrier function assessment is commonly done by measuring transepidermal water loss (TEWL). An important limitation of this method is the influence of intrinsic and extrinsic factors. Electrical impedance spectroscopy (EIS) is a lesser-established method for skin barrier function assessment. Some influential factors have been described, but no guidelines exist regarding the standardization of these measurements.

Objective

To evaluate the effect size of daily routine activities on TEWL and EIS, as well as their correlation with age and anatomical differences.

Methods

Healthy participants (n=31) were stratified into three age groups (18-29, 30-49, and ≥50 years). In a climate-controlled room, EIS and TEWL measurements were performed on the left and right

SUBMITTER: Huygen L 

PROVIDER: S-EPMC10995614 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature