Virulence genes, resistome and mobilome of Streptococcus suis strains isolated in France.

ABSTRACT: Streptococcus suis is a leading cause of infection in pigs, causing extensive economic losses. In addition, it can also infect wild fauna, and can be responsible for severe infections in humans. Increasing antimicrobial resistance (AMR) has been described in S. suis worldwide and most of the AMR genes are carried by mobile genetic elements (MGEs). This contributes to their dissemination by horizontal gene transfer. A collection of 102 strains isolated from humans, pigs and wild boars in France was subjected to whole genome sequencing in order to: (i) study their genetic diversity, (ii) evaluate their content in virulence-associated genes, (iii) decipher the mechanisms responsible for their AMR and their association with MGEs, and (iv) study their ability to acquire extracellu

SUBMITTER: Dechene-Tempier M 

PROVIDER: S-EPMC10995628 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature