UBE2C: A pan-cancer diagnostic and prognostic biomarker revealed through bioinformatics analysis.

ABSTRACT:

Background

The diverse and complex attributes of cancer have made it a daunting challenge to overcome globally and remains to endanger human life. Detection of critical cancer-related gene alterations in solid tumor samples better defines patient diagnosis and prognosis, and indicates what targeted therapies must be administered to improve cancer patients' outcome.

Materials and methods

To identify genes that have aberrant expression across different cancer types, differential expressed genes were detected within the TCGA datasets. Subsequently, the DEGs common to all pan cancers were determined. Furthermore, various methods were employed to gain genetic alterations, co-expression genes network and protein-protein interaction (PPI) network, pathway enrichment analysis of com

SUBMITTER: Jalali P 

PROVIDER: S-EPMC10995712 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature