Case report: Aberrant fecal microbiota composition of an infant diagnosed with prolonged intestinal botulism.

ABSTRACT:

Background

Intestinal botulism is primarily reported in small babies as a condition known as infant botulism. The condition results from the ingestion of environmental or foodborne spores of botulinum neurotoxin (BoNT) producing Clostridia, usually Clostridium botulinum, and subsequent spore germination into active botulinum neurotoxinogenic cultures in the gut. It is generally considered that small babies are susceptible to C. botulinum colonization because of their immature gut microbiota. Yet, it is poorly understood which host factors contribute to the clinical outcome of intestinal botulism. We previously reported a case of infant botulism where the infant recovered clinically in six weeks but continued to secrete C. botulinum cells and/or BoNT in the feces for seven months.

SUBMITTER: Douillard FP 

PROVIDER: S-EPMC10996148 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature