CT-based radiomics nomogram for the pre-operative prediction of lymphovascular invasion in colorectal cancer: a multicenter study.

ABSTRACT:

Objective

To develop and externally validate a CT-based radiomics nomogram for the pre-operative prediction of lymphovascular invasion (LVI) in patients with colorectal cancer (CRC).

Methods

357 patients derived from 2 centers with pathologically confirmed CRC were included in this retrospective study. Two-dimensional (2D) and three-dimensional (3D) radiomics features were extracted from portal venous phase CT images. The least absolute shrinkage and selection operator algorithm and logistic regression were used for constructing 2D and 3D radiomics models. The radiomics nomogram was developed by integrating the radiomics score (rad-score) and the clinical risk factor.

Results

The rad-score was significantly higher in the LVI+ group than in the LVI- group (p < 0

SUBMITTER: Li M 

PROVIDER: S-EPMC10997017 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature